Age Defense Retinol Serum 5x

Advanced anti-aging treatment30 mL / 1 fl oz
Formulated by Dr. Shim Ching, MD Board Certified · Cosmetic Surgeon
4.8 · 826 Google reviews
  • Five forms of vitamin A target visible aging
  • Smooths fine lines, wrinkles & uneven texture
  • Zero retinol irritation, redness or flaking
  • Plastic surgeon-formulated for sensitive skin
Plastic Surgeon Formulated
60-Day Money-Back
Clinically Formulated
Cruelty Free
Fragrance Free
Sensitive Skin Safe
Dr. Shim Ching, MD — Board-Certified Plastic Surgeon
A note from Dr. Ching
Every formula I put my name on solves a real problem I see in my Honolulu clinic. Same standards I hold in surgery. Same level of care I give my own patients.
Shim Ching, MD
Board-Certified Plastic Surgeon · Honolulu
The Science Inside

Powered by Renara™

Renara is ShimChingMD’s proprietary regenerative complex — the anchoring technology behind every formula in this line.

Renara supports skin renewal, hydration, and a healthier-looking complexion over time. It’s the science Dr. Shim Ching built into every product, and the reason this line performs the way it does.

Formulated by a Board-Certified Plastic Surgeon

*Individual results vary.

The Science

How it works.

EPIDERMIS DERMIS HYPODERMIS Retinyl Palmitate Retinol Retinaldehyde Encapsulated Granactive

Five forms of vitamin A. Every layer of skin.

Traditional retinol converts through one pathway and irritates as a byproduct. The 5-Form Retinol blend uses HPR, bakuchiol, retinyl palmitate, retinaldehyde, and encapsulated retinol — each one targeting a different depth of skin, from epidermis to deep dermis. The result is clinical-strength resurfacing and collagen support without the flaking, redness, or purging that drives most people to quit.

Shim Ching MD Age Defense Retinol Serum 5x
Proven Benefits

Proven Benefits of 5-Form Retinol

Traditional retinol irritates because it converts through a single pathway. Dr. Ching's clinical blend of five complementary forms of vitamin A — HPR, bakuchiol, retinyl palmitate, retinaldehyde, and encapsulated retinol — delivers the smoothing, resurfacing, and collagen-supporting benefits of prescription-strength retinoids without the flaking, redness, or purging that drives most people to quit.

  • Reduces the appearance of fine lines and wrinkles
  • Smooths texture and refines pore appearance
  • Supports collagen and elastin production
  • Strengthens the skin barrier against photodamage
KEY INGREDIENTS

The actives behind the formula.

HPR, bakuchiol, retinyl palmitate, and niacinamide — engineered as a complementary 5-form blend that delivers prescription-strength results without prescription-strength irritation.

HPR (Hydroxypinacolone Retinoate)

Next-generation retinoid, eight times more effective than traditional retinol, without the irritation

Bakuchiol

Plant-based retinol alternative that calms while it resurfaces

Retinyl Palmitate

Gentle vitamin A ester that releases slowly for continuous overnight renewal

Niacinamide

Multi-functional nutrient that brightens tone, strengthens barrier, and balances oil

Ingredient detail
WHAT TO EXPECT

Visible Results

Refined Routine
Designed to complement a consistent skincare regimen.
Advanced Retinol
Features our Age Defense Retinol Serum 5X formula.
Thoughtful Care
Formulated for integration into your daily skincare routine.
Long-Term Approach
Retinol is commonly used as part of an ongoing skincare regimen.
Daily skincare routine
PM 3-7 nights per week
How to use

Simple to add to your routine.

Apply 2-3 drops to clean, dry skin in the evening. Follow with moisturizer. Start 2-3 nights per week and build up. Always wear SPF the following day. Avoid the eye area.

PM · 3-7 nights per week
Questions

Frequently asked.

How is this different from traditional retinol?
Traditional retinol converts through a single pathway that produces irritation as a byproduct. Our five-form blend uses complementary vitamin A pathways that bypass the irritation mechanism while still delivering clinical-strength resurfacing and collagen support.
Will I experience purging or flaking?
96% of our users reported zero irritation in clinical testing. The five-form blend is specifically engineered to deliver retinoid benefits without the classic purge period.
How long until I see results?
Most users notice smoother texture within 2 weeks. Significant wrinkle reduction and firming typically appear between weeks 4-8 with consistent nightly use.
Can I use this with Vitamin C?
Yes. Apply Vitamin C in the morning and this retinol serum at night. The two are complementary — Vitamin C protects during the day, retinol renews overnight.
Is this safe for sensitive skin?
Yes. Dr. Ching formulated this specifically for his surgical patients with compromised skin barriers. Start 2-3 nights per week and build tolerance.
How long does one bottle last?
Using 2-3 drops nightly, one 30mL bottle lasts approximately 3-4 months.
Shim Ching MD Age Defense Retinol Serum 5x

Shim Ching MD Age Defense Retinol Serum 5x

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